Sensitive

Asthma in any disease

near LINC02757 · rs7110818

Where this position leads

Condition: Asthma

rs7110818 Condition: Asthma Asthma Condition rs7110818 rs7110818 near LINC027…

What the study found

Who was studied 44,383 European ancestry cases, 260,715 European ancestry controls; replicated in 4,854 European ancestry cases, 33,806 European ancestry controls, 998 Caribbean ancestry cases, 5,835 Caribbean ancestry controls, 3,368 East Asian ancestry cases, 191,045 East Asian ancestry controls.

The effect Each copy of the T allele carried 1.10 times the odds of Asthma in any disease (95% confidence interval 1.08-1.11); p = 1 × 10−36.

How common The T allele had a frequency of about 45% in the people studied.

Where it sits Chromosome 11, band 11q13.5 — between genes, 25.8 kb from LINC02757.

What each result means

C/C No copy of the version the research linked to Asthma in any disease. This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Asthma in any disease. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Asthma in any disease. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs7110818

What is rs7110818?

rs7110818 is a single position in the genome, in or near the near LINC02757 gene. Published research associates it with asthma in any disease. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs7110818 linked to?

On MyGeneLog this position is linked to Asthma. The research behind each link, and its sources, are set out on that condition page.

Does having rs7110818 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs7110818 come from?

GWAS Catalog, Nature communications 2022, PMID:36344522. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Asthma in any disease (rs7110818). MyGeneLog™. https://www.mygenelog.com/variants/rs7110818

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