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Proteoglycan 3 levels

PRG3 · rs7107352

What the study found

Who was studied 10,708 European ancestry individuals.

The effect Each copy of the T allele shifted the measure 0.149 higher (95% confidence interval 0.11-0.19); p = 2 × 10−12.

How common The T allele had a frequency of about 89% in the people studied.

Where it sits Chromosome 11, band 11q12.1 — in an intron of PRG3.

What each result means

C/C No copy of the version the research linked to Proteoglycan 3 levels. This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Proteoglycan 3 levels. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Proteoglycan 3 levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs7107352

What is rs7107352?

rs7107352 is a single position in the genome, in or near the PRG3 gene. Published research associates it with proteoglycan 3 levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs7107352 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs7107352 come from?

GWAS Catalog, Science (New York, N.Y.) 2021, PMID:34648354. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Proteoglycan 3 levels (rs7107352). MyGeneLog™. https://www.mygenelog.com/variants/rs7107352

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