Sensitive

Irritable bowel syndrome

NCAM1 · rs7106434

Where this position leads

Condition: Irritable Bowel Syndrome

rs7106434 Condition: Irritable Bowel Syndrome Irritable Bowel Syndrome Condition rs7106434 rs7106434 NCAM1

What the study found

Who was studied 68,267 European ancestry cases, 860,556 European ancestry controls.

The effect Each copy of the T allele shifted the measure 0.0402 higher; p = 2 × 10−11.

Where it sits Chromosome 11, band 11q23.2 — in an intron of NCAM1.

What each result means

C/C No copy of the version the research linked to Irritable bowel syndrome. This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Irritable bowel syndrome. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Irritable bowel syndrome. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs7106434

What is rs7106434?

rs7106434 is a single position in the genome, in or near the NCAM1 gene. Published research associates it with irritable bowel syndrome. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs7106434 linked to?

On MyGeneLog this position is linked to Irritable Bowel Syndrome. The research behind each link, and its sources, are set out on that condition page.

Does having rs7106434 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs7106434 come from?

GWAS Catalog, Frontiers in psychiatry 2026, PMID:42221328. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Irritable bowel syndrome (rs7106434). MyGeneLog™. https://www.mygenelog.com/variants/rs7106434

← See all variants