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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
Strength of the evidence
1 / 4
Its strongest genetic-study result is p = 10−13, with 1 associations in the GWAS Catalog.
How this is scored
4: ClinVar disease-causing, reviewed by an expert panel or a guideline (3–4 stars). 3: ClinVar, several labs agreeing (2 stars), or a genetic study at p ≤ 10−50. 2: ClinVar from one lab (1 star), or p ≤ 10−20. 1: ClinVar submitted without criteria (0 stars), or genome-wide significance (p ≤ 5×10−8). The higher of the two counts. It says how solid the evidence is, not whether it matters for a particular person.
What the study found
Who was studied 3,834 African American or Afro-Caribbean cases, 110,031 African American or Afro-Caribbean controls, 2,867 Hispanic or Latin American cases, 51,872 Hispanic or Latin American controls, 226 East Asian ancestry cases, 6,143 East Asian ancestry controls, 38,768 European ancestry cases, 359,753 European ancestry controls.
The effect
Each copy of the C allele shifted the measure 0.0587 lower (95% confidence interval 0.044-0.073); p = 3 × 10−13.
How common The C allele had a frequency of about 71% in the people studied.
Where it sits Chromosome 11, band 11q14.3 — in an intron of TYR.
What each result means
C/CTwo copies of the version the research linked to Benign neoplasm of skin (PheCode 216). That is the strongest link of the three results. A link in a study is not a diagnosis.
C/TOne copy of the version the research linked to Benign neoplasm of skin (PheCode 216). That is a smaller link than two copies.
T/TNo copy of the version the research linked to Benign neoplasm of skin (PheCode 216). This is the starting point the study compared everyone against.
Science (New York, N.Y.) · 2024 · PMID 39024449 · open access
Questions about rs7101897
What is rs7101897?
rs7101897 is a single position in the genome, in or near the TYR gene. Published research associates it with benign neoplasm of skin (phecode 216). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs7101897 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs7101897 come from?
GWAS Catalog, Science (New York, N.Y.) 2024, PMID:39024449. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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Quoting this page
Licensed CC BY-NC 4.0: free to read, share and adapt for non-commercial use, naming MyGeneLog™ and linking the exact page. Commercial use, including training or serving a commercial AI system, needs a licence — https://www.mygenelog.com/license
Benign neoplasm of skin (PheCode 216) (rs7101897). MyGeneLog™. https://www.mygenelog.com/variants/rs7101897