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Mean corpuscular hemoglobin

YDJC · rs710177

Where this position leads

Conditions: Blood Cell Counts, Colon Polyp

rs710177 Condition: Blood Cell Counts Blood Cell Counts Condition Condition: Colon Polyp Colon Polyp Condition rs710177 rs710177 YDJC

What the study found

Who was studied 128,028 East Asian ancestry individuals.

The effect Each copy of the G allele shifted the measure 0.0281 lower (95% confidence interval 0.021-0.035); p = 4 × 10−14.

How common The G allele had a frequency of about 48% in the people studied.

Where it sits Chromosome 22, band 22q11.21 — a synonymous change in YDJC.

What each result means

A/A No copy of the version the research linked to Mean corpuscular hemoglobin. This is the starting point the study compared everyone against.
A/G One copy of the version the research linked to Mean corpuscular hemoglobin. That is a smaller link than two copies.
G/G Two copies of the version the research linked to Mean corpuscular hemoglobin. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs710177

What is rs710177?

rs710177 is a single position in the genome, in or near the YDJC gene. Published research associates it with mean corpuscular hemoglobin. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs710177 linked to?

On MyGeneLog this position is linked to Blood Cell Counts, Colon Polyp. The research behind each link, and its sources, are set out on that condition page.

Does having rs710177 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs710177 come from?

GWAS Catalog, Nature genetics 2021, PMID:34594039. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Mean corpuscular hemoglobin (rs710177). MyGeneLog™. https://www.mygenelog.com/variants/rs710177

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