Who was studied 133,471 East Asian ancestry individuals.
The effect
Each copy of the G allele shifted the measure 0.0476 higher (95% confidence interval 0.039-0.056); p = 2 × 10−30.
How common The G allele had a frequency of about 23% in the people studied.
Where it sits Chromosome 10, band 10q22.3 — in an intron of DLG5.
What each result means
C/CPublished research associates this genotype with typical/baseline likelihood of Gamma glutamyl transpeptidase — no copies of the reported risk allele.
C/GPublished research associates this genotype (one copy of the reported risk allele) with an intermediate association with Gamma glutamyl transpeptidase.
G/GPublished research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Gamma glutamyl transpeptidase compared to the general population.
rs7099526 is a single position in the genome, in or near the DLG5 gene. Published research associates it with gamma glutamyl transpeptidase. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs7099526 linked to?
On MyGeneLog this position is linked to Colon Polyp. The research behind each link, and its sources, are set out on that condition page.
Does having rs7099526 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs7099526 come from?
GWAS Catalog, Nature genetics 2021, PMID:34594039. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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