Standard

Diastolic blood pressure

CACNB2 · rs7090956

Where this position leads

Condition: Blood Pressure

rs7090956 Condition: Blood Pressure Blood Pressure Condition rs7090956 rs7090956 CACNB2

What the study found

Who was studied 349,328 British ancestry individuals; replicated in 144,022 European ancestry,African ancestry,Asian ancestry individuals.

The effect Each copy of the A allele shifted the measure 0.02 higher (95% confidence interval 0.016-0.024); p = 1 × 10−13.

Where it sits Chromosome 10, band 10p12.31 — in an intron of CACNB2.

What each result means

A/A Two copies of the version the research linked to Diastolic blood pressure. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Diastolic blood pressure. That is a smaller link than two copies.
G/G No copy of the version the research linked to Diastolic blood pressure. This is the starting point the study compared everyone against.
Source

Questions about rs7090956

What is rs7090956?

rs7090956 is a single position in the genome, in or near the CACNB2 gene. Published research associates it with diastolic blood pressure. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs7090956 linked to?

On MyGeneLog this position is linked to Blood Pressure. The research behind each link, and its sources, are set out on that condition page.

Does having rs7090956 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs7090956 come from?

GWAS Catalog, Nature medicine 2024, PMID:38459180. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Diastolic blood pressure (rs7090956). MyGeneLog™. https://www.mygenelog.com/variants/rs7090956

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