ARID5B · rs7089424
Where this position leads
Condition: Acute Lymphoblastic Leukemia
What the study found
Who was studied 1,949 Latino cases, 8,584 Latino controls, 1,184 European ancestry cases, 3551 European ancestry controls, 130 African American cases, 3,842 African American controls; replicated in 959 European ancestry cases, 2,624 European ancestry controls, 530 Latino cases, 511 Latino controls.
The effect Each copy of the T allele carried 1.64 times the odds of Acute lymphoblastic leukemia (childhood); p = 2 × 10−62.
Where it sits Chromosome 10, band 10q21.2 — in an intron of ARID5B.
rs7089424 is a single position in the genome, in or near the ARID5B gene. Published research associates it with acute lymphoblastic leukemia (childhood). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
On MyGeneLog this position is linked to Acute Lymphoblastic Leukemia. The research behind each link, and its sources, are set out on that condition page.
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
GWAS Catalog, Nat Commun 2018, PMID:29348612. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Acute lymphoblastic leukemia (childhood) (rs7089424). MyGeneLog™. https://www.mygenelog.com/variants/rs7089424