Sensitive

Schizophrenia

MIR1307 · rs7085104

Where this position leads

Condition: Schizophrenia

rs7085104 Condition: Schizophrenia Schizophrenia Condition rs7085104 rs7085104 MIR1307

What the study found

Who was studied 5,001 European ancestry cases, 6,243 European ancestry controls, 8,832 cases, 12,067 controls; replicated in 4,801 European ancestry cases, 4,741 European ancestry controls, 2,612 European and unknown ancestry cases, 15,021 European and unknown ancestry controls, 581 trios.

The effect Each copy of the A allele carried 1.11 times the odds of Schizophrenia (95% confidence interval 1.08-1.14); p = 4 × 10−13.

How common The A allele had a frequency of about 64% in the people studied.

Where it sits Chromosome 10, band 10q24.32 — in an intron of BORCS7-ASMT.

What each result means

A/A Two copies of the version the research linked to Schizophrenia. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Schizophrenia. That is a smaller link than two copies.
G/G No copy of the version the research linked to Schizophrenia. This is the starting point the study compared everyone against.
Source

What people read about alongside this

Papers in Europe PMC whose title or abstract names both this rsID and that subject. A shared paper means somebody wrote about the two together — it is not a claim that this position explains the subject.

Questions about rs7085104

What is rs7085104?

rs7085104 is a single position in the genome, in or near the MIR1307 gene. Published research associates it with schizophrenia. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs7085104 linked to?

On MyGeneLog this position is linked to Schizophrenia. The research behind each link, and its sources, are set out on that condition page.

What do people read about alongside rs7085104?

Subjects that appear in the title or abstract of the same papers as this rsID include blood sugar and insulin (1 papers). A shared paper means somebody wrote about the two together; it is not a claim that this position explains the topic.

Does having rs7085104 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs7085104 come from?

GWAS Catalog, Nat Genet 2013, PMID:23974872. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Schizophrenia (rs7085104). MyGeneLog™. https://www.mygenelog.com/variants/rs7085104

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