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Waist-to-hip ratio adjusted for BMI

ZEB1-AS1 · rs7081678

What the study found

Who was studied up to 113,720 European ancestry men, up to 138,655 European ancestry women.

The effect Each copy of the A allele shifted the measure 0.0417 higher; p = 2 × 10−8.

How common The A allele had a frequency of about 8% in the people studied.

Where it sits Chromosome 10, band 10p11.22 — in an intron of MACORIS.

What each result means

A/A Two copies of the version the research linked to Waist-to-hip ratio adjusted for BMI. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Waist-to-hip ratio adjusted for BMI. That is a smaller link than two copies.
G/G No copy of the version the research linked to Waist-to-hip ratio adjusted for BMI. This is the starting point the study compared everyone against.
Source

Questions about rs7081678

What is rs7081678?

rs7081678 is a single position in the genome, in or near the ZEB1-AS1 gene. Published research associates it with waist-to-hip ratio adjusted for bmi. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs7081678 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs7081678 come from?

GWAS Catalog, PLoS genetics 2015, PMID:26426971. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Waist-to-hip ratio adjusted for BMI (rs7081678). MyGeneLog™. https://www.mygenelog.com/variants/rs7081678

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