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N6-methyllysine levels

GPAM · rs7079286

What the study found

Who was studied 2,466 Black/admixed ancestry individuals; replicated in up to 1,653 European, Hispanic, Asian or Black individuals.

The effect Each copy of the G allele shifted the measure 0.228 lower (95% confidence interval 0.16-0.29); p = 5 × 10−12.

Where it sits Chromosome 10, band 10q25.2 — in an intron of GPAM.

What each result means

G/G Two copies of the version the research linked to N6-methyllysine levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
G/T One copy of the version the research linked to N6-methyllysine levels. That is a smaller link than two copies.
T/T No copy of the version the research linked to N6-methyllysine levels. This is the starting point the study compared everyone against.
Source

Questions about rs7079286

What is rs7079286?

rs7079286 is a single position in the genome, in or near the GPAM gene. Published research associates it with n6-methyllysine levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs7079286 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs7079286 come from?

GWAS Catalog, Nature communications 2022, PMID:35995766. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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N6-methyllysine levels (rs7079286). MyGeneLog™. https://www.mygenelog.com/variants/rs7079286

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