0 112225Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot2Amazon2Apple0China (ByteDance, Huawei, Baidu…)2ByteDance (Doubao)2Others5Total11Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Who was studied 31,964 European ancestry cases, 419,135 European ancestry controls; replicated in 4,611 European ancestry cases, 31,478 European ancestry controls.
The effect
Each copy of the C allele carried 1.08 times the odds of Diverticular disease (95% confidence interval 1.06-1.1); p = 2 × 10−22.
How common The C allele had a frequency of about 52% in the people studied.
Where it sits Chromosome 10, band 10p12.1 — in an intron of GPR158.
What each result means
C/CTwo copies of the version the research linked to Diverticular disease. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/TOne copy of the version the research linked to Diverticular disease. That is a smaller link than two copies.
T/TNo copy of the version the research linked to Diverticular disease. This is the starting point the study compared everyone against.
rs7077800 is a single position in the genome, in or near the GPR158 gene. Published research associates it with diverticular disease. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs7077800 linked to?
On MyGeneLog this position is linked to Diverticular Disease. The research behind each link, and its sources, are set out on that condition page.
Does having rs7077800 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs7077800 come from?
GWAS Catalog, Gut 2019, PMID:30661054. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 112225Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot2Amazon2Apple0China (ByteDance, Huawei, Baidu…)2ByteDance (Doubao)2Others5Total11Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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