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Metabolite levels (N6,N6-dimethyllysine; N6.N6-dimethyllysine)

near PYROXD2 · rs7075655

What the study found

Who was studied 3,343 European, Hispanic or African American individuals; replicated in up to 2,466 African American individuals, up to 15,619 European ancestry individuals, 1,734 Hispanic ancestry children.

The effect Each copy of the G allele shifted the measure 0.841 lower (95% confidence interval 0.79-0.89); p = 7 × 10−223.

How common The G allele had a frequency of about 31% in the people studied.

Where it sits Chromosome 10, band 10q24.2 — between genes, 1.3 kb from PYROXD2.

What each result means

A/A No copy of the version the research linked to Metabolite levels (N6,N6-dimethyllysine; N6.N6-dimethyllysine). This is the starting point the study compared everyone against.
A/G One copy of the version the research linked to Metabolite levels (N6,N6-dimethyllysine; N6.N6-dimethyllysine). That is a smaller link than two copies.
G/G Two copies of the version the research linked to Metabolite levels (N6,N6-dimethyllysine; N6.N6-dimethyllysine). That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs7075655

What is rs7075655?

rs7075655 is a single position in the genome, in or near the near PYROXD2 gene. Published research associates it with metabolite levels (n6,n6-dimethyllysine; n6.n6-dimethyllysine). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs7075655 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs7075655 come from?

GWAS Catalog, Nature communications 2023, PMID:37253714. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

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Metabolite levels (N6,N6-dimethyllysine; N6.N6-dimethyllysine) (rs7075655). MyGeneLog™. https://www.mygenelog.com/variants/rs7075655

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