Standard

Non-HDL cholesterol levels

near M6PRP1 · rs7063103

What the study found

Who was studied 1,238,180 European, East Asian, Hispanic, admixed African or South Asian ancestry individuals; replicated in 1,236 Arab ancestry individuals, 4,362 Asian ancestry individuals, 8,205 Hispanic individuals, 10,657 African ancestry individuals, 22,967 African American individuals, 28,290 South Asian ancestry individuals, 71,410 European ancestry individuals, 160,212 East Asian ancestry individuals.

The effect Each copy of the T allele shifted the measure 0.0304 lower (95% confidence interval 0.027-0.033); p = 2 × 10−86.

How common The T allele had a frequency of about 37% in the people studied.

Where it sits Chromosome X, band Xq23 — between genes, 30.6 kb from M6PRP1.

What each result means

C/C No copy of the version the research linked to Non-HDL cholesterol levels. This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Non-HDL cholesterol levels. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Non-HDL cholesterol levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs7063103

What is rs7063103?

rs7063103 is a single position in the genome, in or near the near M6PRP1 gene. Published research associates it with non-hdl cholesterol levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs7063103 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs7063103 come from?

GWAS Catalog, Genome biology 2022, PMID:36575460. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Non-HDL cholesterol levels (rs7063103). MyGeneLog™. https://www.mygenelog.com/variants/rs7063103

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