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Cardiometabolic multimorbidity

CDKN2A-AS1 · rs7041637

What the study found

Who was studied 14,835 European ancestry cases, 352,312 European ancestry controls.

The effect Each copy of the A allele shifted the measure 0.103 higher (95% confidence interval 0.077-0.13); p = 3 × 10−14.

How common The A allele had a frequency of about 27% in the people studied.

Where it sits Chromosome 9, band 9p21.3 — in an intron of CDKN2A-AS1.

What each result means

A/A Two copies of the version the research linked to Cardiometabolic multimorbidity. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/C One copy of the version the research linked to Cardiometabolic multimorbidity. That is a smaller link than two copies.
C/C No copy of the version the research linked to Cardiometabolic multimorbidity. This is the starting point the study compared everyone against.
Source

Questions about rs7041637

What is rs7041637?

rs7041637 is a single position in the genome, in or near the CDKN2A-AS1 gene. Published research associates it with cardiometabolic multimorbidity. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs7041637 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs7041637 come from?

GWAS Catalog, Clinical genetics 2024, PMID:38409652. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Cardiometabolic multimorbidity (rs7041637). MyGeneLog™. https://www.mygenelog.com/variants/rs7041637

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