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Takayasu arteritis

SVEP1 · rs7038415

Where this position leads

Condition: Takayasu Arteritis

rs7038415 Condition: Takayasu Arteritis Takayasu Arteritis Condition rs7038415 rs7038415 SVEP1

What the study found

Who was studied 286 European ancestry cases, 2,652 European ancestry controls, 76 Han Chinese ancestry cases, 889 Han Chinese ancestry controls, 46 South Asian ancestry cases, 501 South Asian ancestry controls, 683 Turkish ancestry cases, 1,721 Turkish ancestry controls.

The effect Each copy of the A allele carried 1.45 times the odds of Takayasu arteritis; p = 5 × 10−8.

Where it sits Chromosome 9, band 9q31.3 — between genes, 10.3 kb from SVEP1.

What each result means

A/A Two copies of the version the research linked to Takayasu arteritis. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/C One copy of the version the research linked to Takayasu arteritis. That is a smaller link than two copies.
C/C No copy of the version the research linked to Takayasu arteritis. This is the starting point the study compared everyone against.
Source

Questions about rs7038415

What is rs7038415?

rs7038415 is a single position in the genome, in or near the SVEP1 gene. Published research associates it with takayasu arteritis. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs7038415 linked to?

On MyGeneLog this position is linked to Takayasu Arteritis. The research behind each link, and its sources, are set out on that condition page.

Does having rs7038415 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs7038415 come from?

GWAS Catalog, Am J Hum Genet 2020, PMID:33308445. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Takayasu arteritis (rs7038415). MyGeneLog™. https://www.mygenelog.com/variants/rs7038415

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