Standard
Takayasu arteritis
SVEP1 · rs7038415
Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What each result means
A/A
Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Takayasu arteritis compared to the general population.
A/C
Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Takayasu arteritis.
C/C
Published research associates this genotype with typical/baseline likelihood of Takayasu arteritis — no copies of the reported risk allele.
Source
Identification of susceptibility loci for Takayasu arteritis through a large multi-ancestral genome-wide association study
Ortiz-Fernández L,
Saruhan-Direskeneli G,
Alibaz-Oner F,
Kaymaz-Tahra S,
Coit P,
Kong X,
Kiprianos AP,
Maughan RT,
Aydin SZ,
Aksu K,
Keser G,
Kamali S
and 59 more — show all
Inanc M,
Springer J,
Akar S,
Onen F,
Akkoc N,
Khalidi NA,
Koening C,
Karadag O,
Kiraz S,
Forbess L,
Langford CA,
McAlear CA,
Ozbalkan Z,
Yavuz S,
Çetin GY,
Alpay-Kanitez N,
Chung S,
Ates A,
Karaaslan Y,
McKinnon-Maksimowicz K,
Monach PA,
Ozer HTE,
Seyahi E,
Fresko I,
Cefle A,
Seo P,
Warrington KJ,
Ozturk MA,
Ytterberg SR,
Cobankara V,
Onat AM,
Duzgun N,
Bıcakcıgil M,
Yentür SP,
Lally L,
Manfredi AA,
Baldissera E,
Erken E,
Yazici A,
Kısacık B,
Kaşifoğlu T,
Dalkilic E,
Cuthbertson D,
Pagnoux C,
Sreih A,
Reales G,
Wallace C,
Wren JD,
Cunninghame-Graham DS,
Vyse TJ,
Sun Y,
Chen H,
Grayson PC,
Tombetti E,
Jiang L,
Mason JC,
Merkel PA,
Direskeneli H,
Sawalha AH
American journal of human genetics · 2021 · PMID 33308445
Questions about rs7038415
What is rs7038415?
rs7038415 is a single position in the genome, in or near the SVEP1 gene. Published research associates it with takayasu arteritis. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs7038415 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs7038415 come from?
GWAS Catalog, Am J Hum Genet 2020, PMID:33308445. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
← See all variants