Sensitive

Coronary artery disease and LDL cholesterol levels (multivariate analysis)

near BNC2 · rs7033354

Where this position leads

Condition: Coronary Artery Disease

rs7033354 Condition: Coronary Artery Disease Coronary Artery Disease Condition rs7033354 rs7033354 near BNC2

What the study found

Who was studied 122,733 coronary artery disease cases, 424,528 coronary artery disease controls, 188,577 individuals.

The effect The reported allele is T; the catalogue records no effect size ; p = 1 × 10−8.

How common The T allele had a frequency of about 63% in the people studied.

Where it sits Chromosome 9, band 9p22.2 — between genes, 33.9 kb from BNC2.

What each result means

C/C No copy of the version the research linked to Coronary artery disease and LDL cholesterol levels (multivariate analysis). This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Coronary artery disease and LDL cholesterol levels (multivariate analysis). That is a smaller link than two copies.
T/T Two copies of the version the research linked to Coronary artery disease and LDL cholesterol levels (multivariate analysis). That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs7033354

What is rs7033354?

rs7033354 is a single position in the genome, in or near the near BNC2 gene. Published research associates it with coronary artery disease and ldl cholesterol levels (multivariate analysis). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs7033354 linked to?

On MyGeneLog this position is linked to Coronary Artery Disease. The research behind each link, and its sources, are set out on that condition page.

Does having rs7033354 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs7033354 come from?

GWAS Catalog, Circ Genom Precis Med 2018, PMID:30525989. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Coronary artery disease and LDL cholesterol levels (multivariate analysis) (rs7033354). MyGeneLog™. https://www.mygenelog.com/variants/rs7033354

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