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Monocyte percentage of white cells

RP11-108B14.5 · rs703108

Where this position leads

Condition: Blood Cell Counts

rs703108 Condition: Blood Cell Counts Blood Cell Counts Condition rs703108 rs703108 RP11-108B14.5

What the study found

Who was studied 170,494 European ancestry individuals.

The effect Each copy of the T allele shifted the measure 0.0244 higher (95% confidence interval 0.016-0.033); p = 3 × 10−9.

How common The T allele had a frequency of about 25% in the people studied.

Where it sits Chromosome 10, band 10p12.31 — in an intron of EBLN1.

What each result means

C/C Published research associates this genotype with typical/baseline likelihood of Monocyte percentage of white cells — no copies of the reported risk allele.
C/T Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Monocyte percentage of white cells.
T/T Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Monocyte percentage of white cells compared to the general population.
Source

Questions about rs703108

What is rs703108?

rs703108 is a single position in the genome, in or near the RP11-108B14.5 gene. Published research associates it with monocyte percentage of white cells. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs703108 linked to?

On MyGeneLog this position is linked to Blood Cell Counts. The research behind each link, and its sources, are set out on that condition page.

Does having rs703108 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs703108 come from?

GWAS Catalog, Cell 2016, PMID:27863252. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Monocyte percentage of white cells (rs703108). MyGeneLog™. https://www.mygenelog.com/variants/rs703108

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