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Abdominal aortic aneurysm

DAB2IP · rs7025486

Where this position leads

Condition: Abdominal Aortic Aneurysm

rs7025486 Condition: Abdominal Aortic Aneurysm Abdominal Aortic Aneurysm Condition Topic: Heart and circulation Heart and circulation Topic rs7025486 rs7025486 DAB2IP

Solid lines are connections this site curates. Dashed lines mean the two ends share a research paper — worth knowing, and not a claim that one explains the other.

What the study found

Who was studied 1,292 European ancestry cases, 30,503 European ancestry controls; replicated in 3,267 European ancestry cases, 7,451 European ancestry controls.

The effect Each copy of the A allele carried 1.21 times the odds of Abdominal aortic aneurysm (95% confidence interval 1.14-1.28); p = 5 × 10−10.

How common The A allele had a frequency of about 23% in the people studied.

Where it sits Chromosome 9, band 9q33.2 — in an intron of DAB2IP.

What each result means

A/A Two copies of the version the research linked to Abdominal aortic aneurysm. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Abdominal aortic aneurysm. That is a smaller link than two copies.
G/G No copy of the version the research linked to Abdominal aortic aneurysm. This is the starting point the study compared everyone against.
Source

What people read about alongside this

Papers in Europe PMC whose title or abstract names both this rsID and that subject. A shared paper means somebody wrote about the two together — it is not a claim that this position explains the subject.

Questions about rs7025486

What is rs7025486?

rs7025486 is a single position in the genome, in or near the DAB2IP gene. Published research associates it with abdominal aortic aneurysm. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs7025486 linked to?

On MyGeneLog this position is linked to Abdominal Aortic Aneurysm. The research behind each link, and its sources, are set out on that condition page.

What do people read about alongside rs7025486?

Subjects that appear in the title or abstract of the same papers as this rsID include heart and circulation (5 papers), cholesterol and blood fats (2 papers), blood sugar and insulin (1 papers). A shared paper means somebody wrote about the two together; it is not a claim that this position explains the topic.

Does having rs7025486 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs7025486 come from?

GWAS Catalog, Nat Genet 2010, PMID:20622881. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Abdominal aortic aneurysm (rs7025486). MyGeneLog™. https://www.mygenelog.com/variants/rs7025486

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