NEK2 · rs701929
Where this position leads
Condition: Blood Cell Counts
What the study found
Who was studied 116,666 British ancestry individuals.
The effect Each copy of the G allele shifted the measure 0.0245 lower (95% confidence interval 0.017-0.032); p = 3 × 10−9.
Where it sits Chromosome 1, band 1q32.3 — a synonymous change in NEK2.
What ClinVar records
Classification
Benign for Retinitis pigmentosa 67, Retinal dystrophy; criteria provided, multiple submitters, no conflicts (2 of 4 stars, 5 submitters), last evaluated 2026-02-04.
ClinVar record 403228 NM_002497.4(NEK2):c.504T>C (p.His168=)
What this is ClinVar's aggregate record for this position (as of its 2026-09-24 release), not a result about you. A classification describes the variant against the condition named, as laboratories submitted it. Whether a person carries this variant, and what that would mean for them, is a question for a clinical test and a genetic counsellor.
rs701929 is a single position in the genome, in or near the NEK2 gene. Published research associates it with red cell distribution width. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
On MyGeneLog this position is linked to Blood Cell Counts. The research behind each link, and its sources, are set out on that condition page.
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
GWAS Catalog, PLoS One 2017, PMID:28957414. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Red cell distribution width (rs701929). MyGeneLog™. https://www.mygenelog.com/variants/rs701929