A/APublished research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Asthma compared to the general population. (GWAS Catalog, Nat Commun 2020, PMID:32296059)
A/CPublished research associates this genotype (one copy of the reported risk allele) with an intermediate association with Asthma. (GWAS Catalog, Nat Commun 2020, PMID:32296059)
C/CPublished research associates this genotype with typical/baseline likelihood of Asthma — no copies of the reported risk allele. (GWAS Catalog, Nat Commun 2020, PMID:32296059)
Nature communications · 2020 · PMID 32296059 · open access
Questions about rs7014953
What is rs7014953?
rs7014953 is a single position in the genome, in or near the SGK223 gene. Published research associates it with asthma. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs7014953 linked to?
On MyGeneLog this position is linked to Asthma. The research behind each link, and its sources, are set out on that condition page.
Does having rs7014953 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs7014953 come from?
GWAS Catalog, Nat Commun 2020, PMID:32296059. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.