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C-reactive protein levels

PPP1R3B-DT · rs7008413

Where this position leads

Condition: C-Reactive Protein Levels

rs7008413 Condition: C-Reactive Protein Levels C-Reactive Protein Levels Condition rs7008413 rs7008413 PPP1R3B-DT

What the study found

Who was studied 418,642 British ancestry individuals.

The effect Each copy of the A allele shifted the measure 0.0367 higher (95% confidence interval 0.031-0.043); p = 8 × 10−34.

How common The A allele had a frequency of about 88% in the people studied.

Where it sits Chromosome 8, band 8p23.1 — in an intron of PPP1R3B-DT.

What each result means

A/A Two copies of the version the research linked to C-reactive protein levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/C One copy of the version the research linked to C-reactive protein levels. That is a smaller link than two copies.
C/C No copy of the version the research linked to C-reactive protein levels. This is the starting point the study compared everyone against.
Source

Questions about rs7008413

What is rs7008413?

rs7008413 is a single position in the genome, in or near the PPP1R3B-DT gene. Published research associates it with c-reactive protein levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs7008413 linked to?

On MyGeneLog this position is linked to C-Reactive Protein Levels. The research behind each link, and its sources, are set out on that condition page.

Does having rs7008413 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs7008413 come from?

GWAS Catalog, European journal of epidemiology 2020, PMID:31900758. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

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C-reactive protein levels (rs7008413). MyGeneLog™. https://www.mygenelog.com/variants/rs7008413

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