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Who was studied 1,580 European ancestry cases, 6,276 European ancestry controls; replicated in 495 Japanese ancestry cases, 676 Japanese ancestry controls.
The effect
Each copy of the G allele carried 1.24 times the odds of Intracranial aneurysm (95% confidence interval 1.15-1.34); p = 4 × 10−8.
How common The G allele had a frequency of about 35% in the people studied.
Where it sits Chromosome 2, band 2q33.1 — in an intron of BOLL.
What each result means
A/ANo copy of the version the research linked to Intracranial aneurysm. This is the starting point the study compared everyone against.
A/GOne copy of the version the research linked to Intracranial aneurysm. That is a smaller link than two copies.
G/GTwo copies of the version the research linked to Intracranial aneurysm. That is the strongest link of the three results. A link in a study is not a diagnosis.
rs700651 is a single position in the genome, in or near the BOLL gene. Published research associates it with intracranial aneurysm. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs700651 linked to?
On MyGeneLog this position is linked to Intracranial Aneurysm. The research behind each link, and its sources, are set out on that condition page.
Does having rs700651 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs700651 come from?
GWAS Catalog, Nature genetics 2008, PMID:18997786. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 1129Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot0Amazon2Apple0China (ByteDance, Huawei, Baidu…)0Others9Total11Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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