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Who was studied 1,251 Chinese ancestry persistently infected cases, 1,057 Chinese ancestry spontaneously recovered controls; replicated in 3,905 Chinese ancestry persistently infected cases, 3,356 Chinese ancestry spontaneously recovered controls.
The effect
Each copy of the C allele carried 1.28 times the odds of Persistent hepatitis B virus infection (95% confidence interval 1.19-1.37); p = 3 × 10−12.
How common The C allele had a frequency of about 28% in the people studied.
Where it sits Chromosome 8, band 8p21.3 — between genes, 79.1 kb from SNORD3F.
What each result means
C/CTwo copies of the version the research linked to Persistent hepatitis B virus infection. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/TOne copy of the version the research linked to Persistent hepatitis B virus infection. That is a smaller link than two copies.
T/TNo copy of the version the research linked to Persistent hepatitis B virus infection. This is the starting point the study compared everyone against.
Papers in Europe PMC whose title or abstract names both this rsID and that subject. A shared paper means somebody wrote about the two together — it is not a claim that this position explains the subject.
Questions about rs7000921
What is rs7000921?
rs7000921 is a single position in the genome, in or near the INTS10 gene. Published research associates it with persistent hepatitis b virus infection. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs7000921 linked to?
On MyGeneLog this position is linked to Chronic Hepatitis B. The research behind each link, and its sources, are set out on that condition page.
What do people read about alongside rs7000921?
Subjects that appear in the title or abstract of the same papers as this rsID include infection and immunity (2 papers). A shared paper means somebody wrote about the two together; it is not a claim that this position explains the topic.
Does having rs7000921 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs7000921 come from?
GWAS Catalog, Nat Commun 2016, PMID:27244555. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
7 4522125222225Reads by AI crawlersClaude2ChatGPT2Google · Gemini1Perplexity2Meta AI5Microsoft · Copilot2Amazon2Apple2China (ByteDance, Huawei, Baidu…)2ByteDance (Doubao)2Others25Total45Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Quoting this page
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Persistent hepatitis B virus infection (rs7000921). MyGeneLog™. https://www.mygenelog.com/variants/rs7000921