0 252282227Reads by AI crawlersClaude0ChatGPT2Google · Gemini0Perplexity2Meta AI8Microsoft · Copilot2Amazon2Apple2China (ByteDance, Huawei, Baidu…)0Others7Total25Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Who was studied 449,484 European ancestry individuals.
The effect
Each copy of the T allele shifted the measure 6.38 z score lower (95% confidence interval -); p = 2 × 10−10.
Where it sits Chromosome 8, band 8p23.1 — in an intron of XKR6.
What each result means
C/CNo copy of the version the research linked to Neuroticism. This is the starting point the study compared everyone against.
C/TOne copy of the version the research linked to Neuroticism. That is a smaller link than two copies.
T/TTwo copies of the version the research linked to Neuroticism. That is the strongest link of the three results. A link in a study is not a diagnosis.
rs6997997 is a single position in the genome, in or near the XKR6 gene. Published research associates it with neuroticism. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs6997997 linked to?
On MyGeneLog this position is linked to Neuroticism. The research behind each link, and its sources, are set out on that condition page.
Does having rs6997997 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs6997997 come from?
GWAS Catalog, Nat Genet 2018, PMID:29942085. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 252282227Reads by AI crawlersClaude0ChatGPT2Google · Gemini0Perplexity2Meta AI8Microsoft · Copilot2Amazon2Apple2China (ByteDance, Huawei, Baidu…)0Others7Total25Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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