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Who was studied 7,495 European ancestry cases, 71,934 European ancestry controls.
The effect
Each copy of the A allele shifted the measure 0.149 higher (95% confidence interval 0.11-0.19); p = 1 × 10−14.
How common The A allele had a frequency of about 41% in the people studied.
Where it sits Chromosome 8, band 8q11.23 — inside RP1.
What each result means
A/ATwo copies of the version the research linked to Intracranial aneurysm. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/GOne copy of the version the research linked to Intracranial aneurysm. That is a smaller link than two copies.
G/GNo copy of the version the research linked to Intracranial aneurysm. This is the starting point the study compared everyone against.
rs6997005 is a single position in the genome, in or near the SOX17 gene. Published research associates it with intracranial aneurysm. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs6997005 linked to?
On MyGeneLog this position is linked to Intracranial Aneurysm. The research behind each link, and its sources, are set out on that condition page.
Does having rs6997005 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs6997005 come from?
GWAS Catalog, Nature genetics 2020, PMID:33199917. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 523Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot0Amazon2Apple0China (ByteDance, Huawei, Baidu…)0Others3Total5Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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