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Body mass index

MIR124-2 · rs6994670

Where this position leads

Condition: Obesity and Body Weight

rs6994670 Condition: Obesity and Body Weight Obesity and Body Weight Condition rs6994670 rs6994670 MIR124-2

What the study found

Who was studied up to 309,889 European ancestry individuals.

The effect Each copy of the A allele shifted the measure 0.0535 higher (95% confidence interval -); p = 2 × 10−11.

How common The A allele had a frequency of about 97% in the people studied.

Where it sits Chromosome 8, band 8q12.3 — in an intron of LINC01414.

What each result means

A/A Two copies of the version the research linked to Body mass index. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Body mass index. That is a smaller link than two copies.
G/G No copy of the version the research linked to Body mass index. This is the starting point the study compared everyone against.
Source

Questions about rs6994670

What is rs6994670?

rs6994670 is a single position in the genome, in or near the MIR124-2 gene. Published research associates it with body mass index. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs6994670 linked to?

On MyGeneLog this position is linked to Obesity and Body Weight. The research behind each link, and its sources, are set out on that condition page.

Does having rs6994670 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs6994670 come from?

GWAS Catalog, PLoS Genet 2015, PMID:26426971. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Body mass index (rs6994670). MyGeneLog™. https://www.mygenelog.com/variants/rs6994670

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