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Vascular endothelial growth factor levels

ZFPM2 · rs6993770

Stands on its own. Nothing else here links to this position yet — but the page above is the point: what the research found, what each genotype means, and where it came from, in language you can read. Links to conditions, drugs and the senses appear automatically if we write them.

What each result means

A/A Published research associates this genotype with typical/baseline likelihood of Vascular endothelial growth factor levels — no copies of the reported risk allele.

A/T Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Vascular endothelial growth factor levels.

T/T Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Vascular endothelial growth factor levels compared to the general population.

Source

Identification of cis- and trans-acting genetic variants explaining up to half the variation in circulating vascular endothelial growth factor levels

Debette S, Visvikis-Siest S, Chen MH, Ndiaye NC, Song C, Destefano A, Safa R, Azimi Nezhad M, Sawyer D, Marteau JB, Xanthakis V, Siest G

and 11 more — show all

Sullivan L, Pfister M, Smith H, Choi SH, Lamont J, Lind L, Yang Q, Fitzgerald P, Ingelsson E, Vasan RS, Seshadri S

Circulation research · 2011 · PMID 21757650

What people read about alongside this

Cholesterol and blood fats1 Depression and stress1 Brain and memory1

Papers in Europe PMC whose title or abstract names both this rsID and that subject. A shared paper means somebody wrote about the two together — it is not a claim that this position explains the subject.

Questions about rs6993770

What is rs6993770?

rs6993770 is a single position in the genome, in or near the ZFPM2 gene. Published research associates it with vascular endothelial growth factor levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What do people read about alongside rs6993770?

Subjects that appear in the title or abstract of the same papers as this rsID include cholesterol and blood fats (1 papers), depression and stress (1 papers), brain and memory (1 papers). A shared paper means somebody wrote about the two together; it is not a claim that this position explains the topic.

Does having rs6993770 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs6993770 come from?

GWAS Catalog, Circ Res 2011, PMID:21757650. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

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