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Neuroticism

GNL1 · rs6986

Where this position leads

Condition: Neuroticism

rs6986 Condition: Neuroticism Neuroticism Condition rs6986 rs6986 GNL1

What each result means

C/C Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Neuroticism compared to the general population. (GWAS Catalog, Nat Genet 2017, PMID:29255261)
C/G Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Neuroticism. (GWAS Catalog, Nat Genet 2017, PMID:29255261)
G/G Published research associates this genotype with typical/baseline likelihood of Neuroticism — no copies of the reported risk allele. (GWAS Catalog, Nat Genet 2017, PMID:29255261)

Source: GWAS Catalog, Nat Genet 2017, PMID:29255261

Questions about rs6986

What is rs6986?

rs6986 is a single position in the genome, in or near the GNL1 gene. Published research associates it with neuroticism. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs6986 linked to?

On MyGeneLog this position is linked to Neuroticism. The research behind each link, and its sources, are set out on that condition page.

Does having rs6986 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs6986 come from?

GWAS Catalog, Nat Genet 2017, PMID:29255261. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

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