Sensitive

Prostate cancer

POU5F1B · rs6983267

Where this position leads

Condition: Prostate Cancer

rs6983267 Condition: Prostate Cancer Prostate Cancer Condition rs6983267 rs6983267 POU5F1B

What the study found

Who was studied 1,172 European ancestry cases, 1,157 European ancestry controls; replicated in 3,941 European ancestry cases, 3,964 European ancestry controls.

The effect Each copy of the G allele carried 1.28 times the odds of Prostate cancer (95% confidence interval 1.15-1.45); p = 7 × 10−12.

How common The G allele had a frequency of about 53% in the people studied.

Where it sits Chromosome 8, band 8q24.21 — in a non-coding transcript of CASC8.

What each result means

G/G Two copies of the version the research linked to Prostate cancer. That is the strongest link of the three results. A link in a study is not a diagnosis.
G/T One copy of the version the research linked to Prostate cancer. That is a smaller link than two copies.
T/T No copy of the version the research linked to Prostate cancer. This is the starting point the study compared everyone against.
Source

What people read about alongside this

Papers in Europe PMC whose title or abstract names both this rsID and that subject. A shared paper means somebody wrote about the two together — it is not a claim that this position explains the subject.

Questions about rs6983267

What is rs6983267?

rs6983267 is a single position in the genome, in or near the POU5F1B gene. Published research associates it with prostate cancer. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs6983267 linked to?

On MyGeneLog this position is linked to Prostate Cancer. The research behind each link, and its sources, are set out on that condition page.

What do people read about alongside rs6983267?

Subjects that appear in the title or abstract of the same papers as this rsID include blood sugar and insulin (2 papers), alcohol and the flush (1 papers), exercise and muscle (1 papers), infection and immunity (1 papers), natural selection (1 papers). A shared paper means somebody wrote about the two together; it is not a claim that this position explains the topic.

Does having rs6983267 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs6983267 come from?

GWAS Catalog, Nat Genet 2008, PMID:18264096. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Prostate cancer (rs6983267). MyGeneLog™. https://www.mygenelog.com/variants/rs6983267

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