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GLIPR1 protein levels

near THSD7A · rs6977013

Where this position leads

Condition: Celiac Disease

rs6977013 Condition: Celiac Disease Celiac Disease Condition rs6977013 rs6977013 near THSD7A

What the study found

Who was studied 47,745 European ancestry individuals.

The effect Each copy of the G allele shifted the measure 0.555 higher (95% confidence interval 0.4-0.72); p = 4 × 10−12.

How common The G allele had a frequency of about 0% in the people studied.

Where it sits Chromosome 7, band 7p21.3 — between genes, 159.9 kb from THSD7A.

What each result means

A/A No copy of the version the research linked to GLIPR1 protein levels. This is the starting point the study compared everyone against.
A/G One copy of the version the research linked to GLIPR1 protein levels. That is a smaller link than two copies.
G/G Two copies of the version the research linked to GLIPR1 protein levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs6977013

What is rs6977013?

rs6977013 is a single position in the genome, in or near the near THSD7A gene. Published research associates it with glipr1 protein levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs6977013 linked to?

On MyGeneLog this position is linked to Celiac Disease. The research behind each link, and its sources, are set out on that condition page.

Does having rs6977013 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs6977013 come from?

GWAS Catalog, Nature genetics 2025, PMID:39789286. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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GLIPR1 protein levels (rs6977013). MyGeneLog™. https://www.mygenelog.com/variants/rs6977013

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