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Chronotype

FEZF1 · rs6968240

What the study found

Who was studied 449,734 European ancestry individuals; replicated in 248,098 European ancestry individuals.

The effect The reported allele is A; the catalogue records no effect size ; p = 3 × 10−10.

How common The A allele had a frequency of about 42% in the people studied.

Where it sits Chromosome 7, band 7q31.32 — in an intron of FEZF1.

What each result means

A/A Two copies of the version the research linked to Chronotype. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/C One copy of the version the research linked to Chronotype. That is a smaller link than two copies.
C/C No copy of the version the research linked to Chronotype. This is the starting point the study compared everyone against.
Source

Questions about rs6968240

What is rs6968240?

rs6968240 is a single position in the genome, in or near the FEZF1 gene. Published research associates it with chronotype. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs6968240 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs6968240 come from?

GWAS Catalog, Nature communications 2019, PMID:30696823. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Chronotype (rs6968240). MyGeneLog™. https://www.mygenelog.com/variants/rs6968240

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