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Insulin-like growth factor 1 levels

near ADCY1 · rs6958337

What the study found

Who was studied 340,567 European ancestry individuals, 5,974 African ancestry individuals, 7,283 South Asian ancestry individuals.

The effect Each copy of the C allele shifted the measure 0.0345 higher (95% confidence interval 0.026-0.043); p = 3 × 10−15.

Where it sits Chromosome 7, band 7p12.3 — between genes, 1.8 kb from ADCY1.

What each result means

C/C Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Insulin-like growth factor 1 levels compared to the general population.
C/T Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Insulin-like growth factor 1 levels.
T/T Published research associates this genotype with typical/baseline likelihood of Insulin-like growth factor 1 levels — no copies of the reported risk allele.
Source

Questions about rs6958337

What is rs6958337?

rs6958337 is a single position in the genome, in or near the near ADCY1 gene. Published research associates it with insulin-like growth factor 1 levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs6958337 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs6958337 come from?

GWAS Catalog, Nature genetics 2021, PMID:33462484. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Insulin-like growth factor 1 levels (rs6958337). MyGeneLog™. https://www.mygenelog.com/variants/rs6958337

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