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X-12844 levels

AKR1D1 · rs6954846

What the study found

Who was studied 8,809 European ancestry individuals.

The effect Each copy of the G allele shifted the measure 0.148 lower (95% confidence interval 0.11-0.19); p = 2 × 10−15.

Where it sits Chromosome 7, band 7q33 — in an intron of AKR1D1.

What each result means

A/A No copy of the version the research linked to X-12844 levels. This is the starting point the study compared everyone against.
A/G One copy of the version the research linked to X-12844 levels. That is a smaller link than two copies.
G/G Two copies of the version the research linked to X-12844 levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs6954846

What is rs6954846?

rs6954846 is a single position in the genome, in or near the AKR1D1 gene. Published research associates it with x-12844 levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs6954846 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs6954846 come from?

GWAS Catalog, Metabolites 2022, PMID:35050183. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

X-12844 levels (rs6954846). MyGeneLog™. https://www.mygenelog.com/variants/rs6954846

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