C/CPublished research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Response to thiopurine immunosuppressants in inflammatory bowel disease (pancreatitis) (azathioprine and mercaptopurine) compared to the general population.
C/TPublished research associates this genotype (one copy of the reported risk allele) with an intermediate association with Response to thiopurine immunosuppressants in inflammatory bowel disease (pancreatitis) (azathioprine and mercaptopurine).
T/TPublished research associates this genotype with typical/baseline likelihood of Response to thiopurine immunosuppressants in inflammatory bowel disease (pancreatitis) (azathioprine and mercaptopurine) — no copies of the reported risk allele.
rs6935723 is a single position in the genome, in or near the HLA region gene. Published research associates it with response to thiopurine immunosuppressants in inflammatory bowel disease (pancreatitis) (azathioprine and mercaptopurine). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs6935723 linked to?
On MyGeneLog this position is linked to Inflammatory Bowel Disease. The research behind each link, and its sources, are set out on that condition page.
Does having rs6935723 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs6935723 come from?
GWAS Catalog, Nat Genet 2014, PMID:25217962. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.