Standard
Allergic sensitization
MICA · rs6932730
Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What each result means
C/C
Published research associates this genotype with typical/baseline likelihood of Allergic sensitization — no copies of the reported risk allele. (GWAS Catalog, Nat Genet 2013, PMID:23817571)
C/T
Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Allergic sensitization. (GWAS Catalog, Nat Genet 2013, PMID:23817571)
T/T
Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Allergic sensitization compared to the general population. (GWAS Catalog, Nat Genet 2013, PMID:23817571)
Source
Meta-analysis of genome-wide association studies identifies ten loci influencing allergic sensitization
Bønnelykke K,
Matheson MC,
Pers TH,
Granell R,
Strachan DP,
Alves AC,
Linneberg A,
Curtin JA,
Warrington NM,
Standl M,
Kerkhof M,
Jonsdottir I
and 58 more — show all
Bukvic BK,
Kaakinen M,
Sleimann P,
Thorleifsson G,
Thorsteinsdottir U,
Schramm K,
Baltic S,
Kreiner-Møller E,
Simpson A,
St Pourcain B,
Coin L,
Hui J,
Walters EH,
Tiesler CMT,
Duffy DL,
Jones G,
Ring SM,
McArdle WL,
Price L,
Robertson CF,
Pekkanen J,
Pekkanen J,
Tang CS,
Thiering E,
Montgomery GW,
Hartikainen AL,
Dharmage SC,
Husemoen LL,
Herder C,
Kemp JP,
Elliot P,
James A,
Waldenberger M,
Abramson MJ,
Fairfax BP,
Knight JC,
Knight JC,
Gupta R,
Thompson PJ,
Holt P,
Sly P,
Hirschhorn JN,
Blekic M,
Weidinger S,
Hakonarsson H,
Stefansson K,
Heinrich J,
Postma DS,
Custovic A,
Pennell CE,
Pennell CE,
Jarvelin MR,
Koppelman GH,
Timpson N,
Ferreira MA,
Ferreira MA,
Bisgaard H,
Henderson AJ
Nature genetics · 2013 · PMID 23817571
Questions about rs6932730
What is rs6932730?
rs6932730 is a single position in the genome, in or near the MICA gene. Published research associates it with allergic sensitization. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs6932730 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs6932730 come from?
GWAS Catalog, Nat Genet 2013, PMID:23817571. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
← See all variants