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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 205,354 European ancestry individuals.
The effect
Each copy of the T allele shifted the measure 0.0224 years higher (95% confidence interval 0.016-0.029); p = 5 × 10−12.
Where it sits Chromosome 6, band 6p21.1 — in an intron of PRICKLE4.
What each result means
C/CNo copy of the version the research linked to Male puberty timing (age at voice breaking MTAG). This is the starting point the study compared everyone against.
C/TOne copy of the version the research linked to Male puberty timing (age at voice breaking MTAG). That is a smaller link than two copies.
T/TTwo copies of the version the research linked to Male puberty timing (age at voice breaking MTAG). That is the strongest link of the three results. A link in a study is not a diagnosis.
Nature communications · 2020 · PMID 32210231 · open access
Questions about rs6925777
What is rs6925777?
rs6925777 is a single position in the genome, in or near the PRICKLE4 gene. Published research associates it with male puberty timing (age at voice breaking mtag). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs6925777 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs6925777 come from?
GWAS Catalog, Nature communications 2020, PMID:32210231. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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Quoting this page
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Male puberty timing (age at voice breaking MTAG) (rs6925777). MyGeneLog™. https://www.mygenelog.com/variants/rs6925777