Standard

Urinary calculus (PheCode 594)

near FTH1P5 · rs6923215

What the study found

Who was studied 5,904 African American or Afro-Caribbean cases, 112,267 African American or Afro-Caribbean controls, 4,320 Hispanic or Latin American cases, 53,566 Hispanic or Latin American controls, 393 East Asian ancestry cases, 6,300 East Asian ancestry controls, 39,380 European ancestry cases, 394,076 European ancestry controls.

The effect Each copy of the G allele shifted the measure 0.0569 lower (95% confidence interval 0.042-0.072); p = 2 × 10−12.

How common The G allele had a frequency of about 69% in the people studied.

Where it sits Chromosome 6, band 6p12.3 — between genes, 8.9 kb from FTH1P5.

What each result means

A/A No copy of the version the research linked to Urinary calculus (PheCode 594). This is the starting point the study compared everyone against.
A/G One copy of the version the research linked to Urinary calculus (PheCode 594). That is a smaller link than two copies.
G/G Two copies of the version the research linked to Urinary calculus (PheCode 594). That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs6923215

What is rs6923215?

rs6923215 is a single position in the genome, in or near the near FTH1P5 gene. Published research associates it with urinary calculus (phecode 594). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs6923215 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs6923215 come from?

GWAS Catalog, Science (New York, N.Y.) 2024, PMID:39024449. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Urinary calculus (PheCode 594) (rs6923215). MyGeneLog™. https://www.mygenelog.com/variants/rs6923215

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