0 22Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot0Amazon0Apple0China (ByteDance, Huawei, Baidu…)0Others2Total2Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 1,926 European ancestry cases, 2,938 European ancestry controls; replicated in 875 European ancestry cases, 1,644 European ancestry controls.
The effect
Each copy of the A allele carried 1.23 times the odds of Coronary heart disease (95% confidence interval 1.15-1.33); p = 3 × 10−8.
How common The A allele had a frequency of about 25% in the people studied.
Where it sits Chromosome 6, band 6q25.1 — in an intron of MTHFD1L.
What each result means
A/ATwo copies of the version the research linked to Coronary heart disease. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/GOne copy of the version the research linked to Coronary heart disease. That is a smaller link than two copies.
G/GNo copy of the version the research linked to Coronary heart disease. This is the starting point the study compared everyone against.
The New England journal of medicine · 2007 · PMID 17634449
Questions about rs6922269
What is rs6922269?
rs6922269 is a single position in the genome, in or near the MTHFD1L gene. Published research associates it with coronary heart disease. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs6922269 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs6922269 come from?
GWAS Catalog, The New England journal of medicine 2007, PMID:17634449. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 22Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot0Amazon0Apple0China (ByteDance, Huawei, Baidu…)0Others2Total2Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Quoting this page
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.