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Interleukin-1-beta levels

HLA · rs6917603

What the study found

Who was studied 13,577 Finnish ancestry individuals.

The effect Each copy of the C allele shifted the measure 0.163 lower; p = 2 × 10−12.

How common The C allele had a frequency of about 25% in the people studied.

Where it sits Chromosome 6, band 6p22.1 — in an intron of POLR1HASP.

What each result means

C/C Two copies of the version the research linked to Interleukin-1-beta levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/T One copy of the version the research linked to Interleukin-1-beta levels. That is a smaller link than two copies.
T/T No copy of the version the research linked to Interleukin-1-beta levels. This is the starting point the study compared everyone against.
Source

Questions about rs6917603

What is rs6917603?

rs6917603 is a single position in the genome, in or near the HLA gene. Published research associates it with interleukin-1-beta levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs6917603 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs6917603 come from?

GWAS Catalog, Journal of medical genetics 2019, PMID:31217265. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Interleukin-1-beta levels (rs6917603). MyGeneLog™. https://www.mygenelog.com/variants/rs6917603

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