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Insomnia

ITPR3 · rs6915136

Where this position leads

Condition: Insomnia

rs6915136 Condition: Insomnia Insomnia Condition rs6915136 rs6915136 ITPR3

What the study found

Who was studied 390,751 European ancestry female cases, 1,018,386 European ancestry female controls.

The effect Each copy of the T allele shifted the measure 0.013 lower (95% confidence interval 0.0091-0.0169); p = 3 × 10−15.

Where it sits Chromosome 6, band 6p21.31 — in an intron of ITPR3.

What each result means

C/C Published research associates this genotype with typical/baseline likelihood of Insomnia — no copies of the reported risk allele.
C/T Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Insomnia.
T/T Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Insomnia compared to the general population.
Source

Questions about rs6915136

What is rs6915136?

rs6915136 is a single position in the genome, in or near the ITPR3 gene. Published research associates it with insomnia. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs6915136 linked to?

On MyGeneLog this position is linked to Insomnia. The research behind each link, and its sources, are set out on that condition page.

Does having rs6915136 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs6915136 come from?

GWAS Catalog, Nature genetics 2022, PMID:35835914. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Insomnia (rs6915136). MyGeneLog™. https://www.mygenelog.com/variants/rs6915136

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