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Platelet count in pregnancy

near Metazoa_SRP · rs6914422

What the study found

Who was studied 98,500 Chinese ancestry individuals; replicated in 47,047 Chinese ancestry individuals.

The effect Each copy of the T allele shifted the measure 0.0699 higher (95% confidence interval 0.053-0.087); p = 2 × 10−16.

How common The T allele had a frequency of about 29% in the people studied.

Where it sits Chromosome 6, band 6p21.31 — between genes, 4 kb from Metazoa_SRP.

What each result means

C/C No copy of the version the research linked to Platelet count in pregnancy. This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Platelet count in pregnancy. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Platelet count in pregnancy. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs6914422

What is rs6914422?

rs6914422 is a single position in the genome, in or near the near Metazoa_SRP gene. Published research associates it with platelet count in pregnancy. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs6914422 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs6914422 come from?

GWAS Catalog, Nature genetics 2026, PMID:42509370. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Platelet count in pregnancy (rs6914422). MyGeneLog™. https://www.mygenelog.com/variants/rs6914422

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