Sensitive

Bladder cancer

CDKAL1 · rs6910215

Where this position leads

Condition: Bladder Cancer

rs6910215 Condition: Bladder Cancer Bladder Cancer Condition rs6910215 rs6910215 CDKAL1

What the study found

Who was studied 30,156 European ancestry cases, 1,527,568 European ancestry controls.

The effect Each copy of the C allele carried 1.08 times the odds of Bladder cancer (95% confidence interval 1.05791453055237-1.0976236735187); p = 3 × 10−15.

How common The C allele had a frequency of about 57% in the people studied.

Where it sits Chromosome 6, band 6p22.3 — in an intron of CDKAL1.

What each result means

C/C Two copies of the version the research linked to Bladder cancer. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/T One copy of the version the research linked to Bladder cancer. That is a smaller link than two copies.
T/T No copy of the version the research linked to Bladder cancer. This is the starting point the study compared everyone against.
Source

Questions about rs6910215

What is rs6910215?

rs6910215 is a single position in the genome, in or near the CDKAL1 gene. Published research associates it with bladder cancer. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs6910215 linked to?

On MyGeneLog this position is linked to Bladder Cancer. The research behind each link, and its sources, are set out on that condition page.

Does having rs6910215 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs6910215 come from?

GWAS Catalog, Nature communications 2026, PMID:42706231. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Bladder cancer (rs6910215). MyGeneLog™. https://www.mygenelog.com/variants/rs6910215

← See all variants