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Who was studied 315,133 European ancestry individuals, 74,970 East Asian ancestry individuals.
The effect
Each copy of the C allele shifted the measure 0.0278 lower (95% confidence interval 0.023-0.032); p = 4 × 10−36.
Where it sits Chromosome 6, band 6p21.33 — between genes, 20.3 kb from HLA-B.
What each result means
A/ANo copy of the version the research linked to HDL cholesterol. This is the starting point the study compared everyone against.
A/COne copy of the version the research linked to HDL cholesterol. That is a smaller link than two copies.
C/CTwo copies of the version the research linked to HDL cholesterol. That is the strongest link of the three results. A link in a study is not a diagnosis.
rs6908001 is a single position in the genome, in or near the near HLA-B gene. Published research associates it with hdl cholesterol. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs6908001 linked to?
On MyGeneLog this position is linked to Cholesterol (LDL, HDL and Total). The research behind each link, and its sources, are set out on that condition page.
Does having rs6908001 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs6908001 come from?
GWAS Catalog, Nature genetics 2021, PMID:34594039. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 11218Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot0Amazon2Apple1China (ByteDance, Huawei, Baidu…)0Others8Total11Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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