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Tryptophan levels

MFSD4B-DT · rs6901004

What the study found

Who was studied 7,804 European ancestry individuals.

The effect Each copy of the C allele shifted the measure 0.006 lower (95% confidence interval -0.004--0.008); p = 1 × 10−11.

How common The C allele had a frequency of about 57% in the people studied.

Where it sits Chromosome 6, band 6q21 — in an intron of MFSD4B-DT.

What each result means

C/C Two copies of the version the research linked to Tryptophan levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/G One copy of the version the research linked to Tryptophan levels. That is a smaller link than two copies.
G/G No copy of the version the research linked to Tryptophan levels. This is the starting point the study compared everyone against.
Source

Questions about rs6901004

What is rs6901004?

rs6901004 is a single position in the genome, in or near the MFSD4B-DT gene. Published research associates it with tryptophan levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs6901004 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs6901004 come from?

GWAS Catalog, Nature genetics 2014, PMID:24816252. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Tryptophan levels (rs6901004). MyGeneLog™. https://www.mygenelog.com/variants/rs6901004

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