Standard
Primary biliary cholangitis
IL7R · rs6890853
Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What each result means
A/A
Published research associates this genotype with typical/baseline likelihood of Primary biliary cholangitis — no copies of the reported risk allele.
A/G
Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Primary biliary cholangitis.
G/G
Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Primary biliary cholangitis compared to the general population.
Source
Genome-wide association study identifies TNFSF15 and POU2AF1 as susceptibility loci for primary biliary cirrhosis in the Japanese population
Nakamura M,
Nishida N,
Kawashima M,
Aiba Y,
Tanaka A,
Yasunami M,
Nakamura H,
Komori A,
Nakamuta M,
Zeniya M,
Hashimoto E,
Ohira H
and 68 more — show all
Yamamoto K,
Onji M,
Kaneko S,
Honda M,
Yamagiwa S,
Nakao K,
Ichida T,
Takikawa H,
Seike M,
Umemura T,
Ueno Y,
Sakisaka S,
Kikuchi K,
Ebinuma H,
Yamashiki N,
Tamura S,
Sugawara Y,
Mori A,
Yagi S,
Shirabe K,
Taketomi A,
Arai K,
Monoe K,
Ichikawa T,
Taniai M,
Miyake Y,
Kumagi T,
Abe M,
Yoshizawa K,
Joshita S,
Shimoda S,
Honda K,
Takahashi H,
Hirano K,
Takeyama Y,
Harada K,
Migita K,
Ito M,
Yatsuhashi H,
Fukushima N,
Ota H,
Komatsu T,
Saoshiro T,
Ishida J,
Kouno H,
Kouno H,
Yagura M,
Kobayashi M,
Muro T,
Masaki N,
Hirata K,
Watanabe Y,
Nakamura Y,
Shimada M,
Hirashima N,
Komeda T,
Sugi K,
Koga M,
Ario K,
Takesaki E,
Maehara Y,
Uemoto S,
Kokudo N,
Tsubouchi H,
Mizokami M,
Nakanuma Y,
Tokunaga K,
Ishibashi H
American journal of human genetics · 2012 · PMID 23000144
Questions about rs6890853
What is rs6890853?
rs6890853 is a single position in the genome, in or near the IL7R gene. Published research associates it with primary biliary cholangitis. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs6890853 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs6890853 come from?
GWAS Catalog, Am J Hum Genet 2012, PMID:23000144. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
← See all variants