1 181412226Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity1Meta AI4Microsoft · Copilot1Amazon2Apple2China (ByteDance, Huawei, Baidu…)2ByteDance (Doubao)2Others6Total18Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Who was studied 628 European ancestry cases, 7,352 European ancestry controls.
The effect
Each copy of the A allele carried 1.91 times the odds of Classic bladder exstrophy (95% confidence interval 1.68-2.16); p = 6 × 10−24.
Where it sits Chromosome 5, band 5q11.2 — between genes, 3.7 kb from HMGB1P47.
What each result means
A/ATwo copies of the version the research linked to Classic bladder exstrophy. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/TOne copy of the version the research linked to Classic bladder exstrophy. That is a smaller link than two copies.
T/TNo copy of the version the research linked to Classic bladder exstrophy. This is the starting point the study compared everyone against.
Communications biology · 2022 · PMID 36352089 · open access
Questions about rs6874700
What is rs6874700?
rs6874700 is a single position in the genome, in or near the near HMGB1P47 gene. Published research associates it with classic bladder exstrophy. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs6874700 linked to?
On MyGeneLog this position is linked to Classic Bladder Exstrophy. The research behind each link, and its sources, are set out on that condition page.
Does having rs6874700 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs6874700 come from?
GWAS Catalog, Communications biology 2022, PMID:36352089. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
1 181412226Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity1Meta AI4Microsoft · Copilot1Amazon2Apple2China (ByteDance, Huawei, Baidu…)2ByteDance (Doubao)2Others6Total18Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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