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High-density lipoprotein levels (MTAG)

TIMD4 · rs6873413

What the study found

Who was studied 125,000 African ancestry individuals (MTAG boosted by total cholesterol and triglyceride samples).

The effect Each copy of the T allele shifted the measure 0.0437 higher (95% confidence interval 0.033-0.054); p = 4 × 10−17.

Where it sits Chromosome 5, band 5q33.3 — in an intron of TIMD4.

What each result means

C/C No copy of the version the research linked to High-density lipoprotein levels (MTAG). This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to High-density lipoprotein levels (MTAG). That is a smaller link than two copies.
T/T Two copies of the version the research linked to High-density lipoprotein levels (MTAG). That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs6873413

What is rs6873413?

rs6873413 is a single position in the genome, in or near the TIMD4 gene. Published research associates it with high-density lipoprotein levels (mtag). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs6873413 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs6873413 come from?

GWAS Catalog, Nature communications 2023, PMID:37669986. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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High-density lipoprotein levels (MTAG) (rs6873413). MyGeneLog™. https://www.mygenelog.com/variants/rs6873413

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