near TXNL1 · rs686781
Where this position leads
What the study found
Who was studied 205,327 European ancestry males.
The effect Each copy of the A allele shifted the measure 0.0255 lower (95% confidence interval 0.019-0.033); p = 7 × 10−13.
How common The A allele had a frequency of about 25% in the people studied.
Where it sits Chromosome 18, band 18q21.31 — between genes, 28.1 kb from TXNL1.
rs686781 is a single position in the genome, in or near the near TXNL1 gene. Published research associates it with male-pattern baldness. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
On MyGeneLog this position is linked to Androgenetic Alopecia (Male Pattern Baldness). The research behind each link, and its sources, are set out on that condition page.
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
GWAS Catalog, Nat Commun 2018, PMID:30573740. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Male-pattern baldness (rs686781). MyGeneLog™. https://www.mygenelog.com/variants/rs686781