Sensitive
Serum metabolite ratios in chronic kidney disease
BTBD3 · rs686548
Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What each result means
A/A
Published research associates this genotype with typical/baseline likelihood of Serum metabolite ratios in chronic kidney disease — no copies of the reported risk allele.
A/T
Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Serum metabolite ratios in chronic kidney disease.
T/T
Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Serum metabolite ratios in chronic kidney disease compared to the general population.
Source
Genome-Wide Association Studies of Metabolites in Patients with CKD Identify Multiple Loci and Illuminate Tubular Transport Mechanisms
Li Y,
Sekula P,
Wuttke M,
Wahrheit J,
Hausknecht B,
Schultheiss UT,
Gronwald W,
Schlosser P,
Tucci S,
Ekici AB,
Spiekerkoetter U,
Kronenberg F
and 3 more — show all
Journal of the American Society of Nephrology : JASN · 2018 · PMID 29545352
Questions about rs686548
What is rs686548?
rs686548 is a single position in the genome, in or near the BTBD3 gene. Published research associates it with serum metabolite ratios in chronic kidney disease. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs686548 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs686548 come from?
GWAS Catalog, J Am Soc Nephrol 2018, PMID:29545352. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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